Interactor 1: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Interactor 2: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 15196016, 11526232, 10716984
Identification Methods x-ray crystallography, pull down, cosedimentation through density gradient
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ribonuc_red_sm~Ribonuc_red_sm
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0009263 - deoxyribonucleotide biosynthetic process
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 345
Sc

1 345
+ Hs
+ Hs
+ Hs
+ Sc
+ Vv
+ Sc
+ Ce
+ Hh
+ Hh
+ Ha
+ Hh
+ Ec
+ Ec
+ Mp
+ Mt

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Last updated: 15 Jul 2024