Interactor 1: MCM2 (P49735)
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)
Gene: MCM2

Interactor 2: MCM4 (Q26454)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Protein disc proliferation abnormal)
Gene: dpa

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 11726693, 8688561
Identification Methods anti bait coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006260 - DNA replication
and 7 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 887
Dm

1 866
+ Xl
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Xl
+ Xl
+ Xl
+ Hs
+ Hs
+ Sp
+ At
+ Hs
+ Sp
+ Xl
+ Xl
+ Hs

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Last updated: 15 Jul 2024