Interactor 1: MCM2 (P49735)
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)
Gene: MCM2

Interactor 2: MCM5 (Q9VGW6)
DNA replication licensing factor Mcm5 (EC 3.6.4.12) (Minichromosome maintenance 5 protein) (DmMCM5)
Gene: MCM5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 11024168, 16798881, 25117490, 22036573, 11726693
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006279 - premeiotic DNA replication
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 887
Dm

1 733
+ Hs
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+ Xl
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+ Dm
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+ Xl
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+ At
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+ Sp
+ Xl
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+ Xl

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Last updated: 15 Jul 2024