Interactor 1: MCM2 (P49735)
DNA replication licensing factor Mcm2 (EC 3.6.4.12) (Minichromosome maintenance 2 protein) (DmMCM2)
Gene: MCM2

Interactor 2: MCM3 (Q9XYU1)
DNA replication licensing factor Mcm3 (EC 3.6.4.12) (Minichromosome maintenance 3 protein) (DmMCM3)
Gene: MCM3

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 21378962, 25117490, 11726693
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006279 - premeiotic DNA replication
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 887
Dm

1 819
+ Xl
+ Mm
+ Hs
+ Xl
+ Hs
+ Dm
+ Dm
+ Xl
+ Xl
+ Hs
+ Dm
+ Hs
+ Hs
+ Xl
+ Hs
+ Sp
+ At
+ Xl
+ Xl
+ Sp

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Last updated: 15 Jul 2024