HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 25963833, 12614612
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM2_N~MCM2_N, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003688 - DNA replication origin binding
and 23 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 904
Hs

1 904
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Xl
+ Xl
+ Xl
+ Dm
+ Dm
+ Sp
+ At
+ Xl
+ Xl
+ Xl
+ Sp

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Last updated: 15 Jul 2024