HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 377
+	Hs
		832507 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTBL_HUMAN (4-377): 0: 712: 87.97
+	Hs
		832346 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		832350 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		832353 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTS_HUMAN (1-377): 0: 598: 97.88
+	Hs
		832347 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTH_HUMAN (4-377): 0: 591: 99.20
+	Hs
		708670 MCM5_HUMAN (169-902): 0: 768: 29.43		ACTBL_HUMAN (4-377): 0: 712: 87.97
+	Sc
		667878 MCM5_YEAST (170-875): 0: 723: 28.23		ACT_YEAST (4-377): 0: 643: 86.63