Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 25963833, 19862764, 28514442, 27248496, 33961781, 26167883
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~MCM2_N
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006334 - nucleosome assembly
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 904
Hs

1 103
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024