HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: MCMBP (Q9BTE3)
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)
Gene: MCMBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	25963833, 33961781, 22540012, 25036637, 24299456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 642
+	Hs
		708504 MCM4_HUMAN (2-885): 0: 847: 28.42		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		708753 MCM5_HUMAN (169-902): 0: 768: 29.43		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		627347 MCM3_HUMAN (186-897): 0: 725: 29.20		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		1312152 MCM8_HUMAN (119-856): 0: 721: 28.81		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Mm
		627414 MCM3_MOUSE (186-897): 0: 725: 28.80		MCMBP_MOUSE (1-642): 0: 998: 92.99
+	Hs
		1055618 MCM6_HUMAN (186-817): 0: 710: 31.18		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	Hs
		709032 MCM7_HUMAN (188-886): 0: 707: 27.35		MCMBP_HUMAN (1-642): 0: 1009: 100.00
+	At
		1119356 MCM2_ARATH (14-900): 0: 901: 47.95		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Dm
		1366520 MCM5_DROME (195-902): 0: 745: 30.39		MCMBP_DROME (1-632): 0: 724: 35.47
+	At
		1013294 MCM4_ARATH (75-875): 0: 753: 26.98		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Dm
		1370623 MCM3_DROME (187-884): 0: 710: 31.08		MCMBP_DROME (1-632): 0: 724: 35.47
+	At
		1119353 MCM3_ARATH (189-891): 0: 740: 31.38		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		795006 MCM7_ARATH (200-886): 0: 722: 29.49		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		99162 MCM6_ARATH (183-900): 0: 722: 27.87		MCMBP_ARATH (4-632): 0: 685: 31.38
+	At
		285822 MCM5_ARATH (198-903): 0: 709: 29.47		MCMBP_ARATH (4-632): 0: 685: 31.38
+	Sp
		293433 MCM2_SCHPO (17-822): 0: 869: 50.85		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		293431 MCM4_SCHPO (12-896): 0: 757: 26.02		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		293434 MCM5_SCHPO (184-828): 0: 718: 29.99		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09
+	Sp
		293432 MCM3_SCHPO (199-798): 1.84e-97: 327: 34.95		YFF4_SCHPO (341-623): 6.68e-102: 321: 25.09