HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: DONS (Q9NYP3)
Protein downstream neighbor of Son (B17)
Gene: DONSON

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28191891, 32769987
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006260 - DNA replication
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 566
+	Hs
		708529 MCM4_HUMAN (2-885): 0: 847: 28.42		DONS_HUMAN (1-566): 0: 851: 100.00
+	Hs
		708788 MCM5_HUMAN (169-902): 0: 768: 29.43		DONS_HUMAN (1-566): 0: 851: 100.00
+	Hs
		1348590 MCM8_HUMAN (119-856): 0: 721: 28.81		DONS_HUMAN (1-566): 0: 851: 100.00
+	Hs
		1055643 MCM6_HUMAN (186-817): 0: 710: 31.18		DONS_HUMAN (1-566): 0: 851: 100.00
+	Hs
		709085 MCM7_HUMAN (188-886): 0: 707: 27.35		DONS_HUMAN (1-566): 0: 851: 100.00