HitPredict

Interactor 1: TMEDA (P49755)
Transmembrane emp24 domain-containing protein 10 (Protein TMED10) (21 kDa transmembrane-trafficking protein) (S31I125) (S31III125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta)
Gene: TMED10

Interactor 2: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	27342126, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 297
+	Hs
		1062649 TMED9_HUMAN (8-218): 4.55e-80: 241: 29.96		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		1062559 TMED4_HUMAN (29-218): 1.57e-77: 234: 32.84		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		1062520 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		1062719 TMED5_HUMAN (24-216): 5.38e-56: 179: 17.16		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00