HitPredict

Interactor 1: TMEDA (P49755)
Transmembrane emp24 domain-containing protein 10 (Protein TMED10) (21 kDa transmembrane-trafficking protein) (S31I125) (S31III125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta)
Gene: TMED10

Interactor 2: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	9472029
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006886 - intracellular protein transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 767
+	Hs
		1074075 TMED9_HUMAN (8-218): 4.55e-80: 241: 29.96		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		833225 TMEDA_HUMAN (1-219): 4.49e-84: 250: 100.00		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		1073994 TMED9_HUMAN (8-218): 4.55e-80: 241: 29.96		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		1071768 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		1074029 TMED7_HUMAN (26-216): 2.43e-70: 215: 23.56		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		1071767 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		1074030 TMED3_HUMAN (29-218): 5.18e-65: 202: 20.94		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Sc
		546705 EMP24_YEAST (14-218): 5.13e-61: 191: 26.57		SEC23_YEAST (9-764): 0: 860: 49.94
+	Sc
		546788 ERP1_YEAST (16-218): 9.62e-59: 185: 19.72		SEC23_YEAST (9-764): 0: 860: 49.94
+	Sc
		546775 TMEDA_YEAST (18-218): 2.52e-57: 182: 35.75		SEC23_YEAST (9-764): 0: 860: 49.94
+	Hs
		315702 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		867099 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC24C_HUMAN (2-721): 0: 570: 16.67
+	Hs
		315559 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC24A_HUMAN (4-760): 0: 559: 19.20
+	Hs
		297861 TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53		SC24D_HUMAN (9-680): 0: 557: 16.78
+	Sc
		698422 EMP24_YEAST (14-218): 5.13e-61: 191: 26.57		SEC24_YEAST (10-663): 1.02e-168: 511: 15.04
+	Sc
		774447 ERP1_YEAST (16-218): 9.62e-59: 185: 19.72		SEC24_YEAST (10-663): 1.02e-168: 511: 15.04
+	Sc
		774432 TMEDA_YEAST (18-218): 2.52e-57: 182: 35.75		SEC24_YEAST (10-663): 1.02e-168: 511: 15.04