HitPredict

Interactor 1: H2A1B (C0HKE1)
Histone H2A type 1-B
Gene: H2ac4

Interactor 2: AIRE (Q9Z0E3)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)
Gene: AIRE

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20085707
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Mm			1 552
+	Hs
		217498 H2A1C_HUMAN (1-130): 3.23e-68: 203: 98.46		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		217435 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		391675 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		1018640 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		470359 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		KMT2A_HUMAN (101-552): 8.12e-36: 145: 12.24
+	Hs
		391662 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		KMT2A_HUMAN (101-552): 8.12e-36: 145: 12.24
+	Hs
		470387 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		391704 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		1059795 H2A1H_HUMAN (1-128): 1.81e-67: 201: 98.44		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		391802 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		KMT2C_HUMAN (285-552): 1.18e-23: 108: 14.59
+	Hs
		1059717 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		555434 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BPTF_HUMAN (278-392): 1.33e-25: 114: 25.22
+	Hs
		1059647 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		331703 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35
+	Hs
		331860 H2A1C_HUMAN (1-130): 3.23e-68: 203: 98.46		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35
+	Hs
		331824 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35
+	Hs
		299030 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		PHF14_HUMAN (128-371): 5.7e-09: 61: 14.52
+	Hs
		299066 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		PHF14_HUMAN (128-371): 5.7e-09: 61: 14.52
+	Hs
		299027 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		PHF14_HUMAN (128-371): 5.7e-09: 61: 14.52
+	Hs
		299035 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		PHF14_HUMAN (128-371): 5.7e-09: 61: 14.52