HitPredict

Interactor 1: RBM25 (P49756)
RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)
Gene: RBM25

Interactor 2: PR40B (Q6NWY9)
Pre-mRNA-processing factor 40 homolog B (Huntingtin yeast partner C) (Huntingtin-interacting protein C)
Gene: PRPF40B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 843 Hs			1 871
+	Hs
		263562 RBM25_HUMAN (1-843): 8.68e-63: 229: 100.00		PR40A_HUMAN (5-871): 2.94e-154: 479: 49.68
+	Dm
		1359339 Q9V3Y5_DROME (154-841): 3.42e-25: 114: 20.20		Q9VQK5_DROME (37-870): 5.6e-167: 507: 38.83
+	Hs
		808399 RBM25_HUMAN (1-843): 8.68e-63: 229: 100.00		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		1078893 ITSN1_HUMAN (394-779): 1.8e-11: 70.2: 12.34		ITCH_HUMAN (34-369): 2.25e-61: 226: 13.22
+	Hs
		808780 BD1L1_HUMAN (166-744): 5.22e-24: 111: 12.59		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		808806 PHF3_HUMAN (280-432): 6.42e-20: 98.1: 25.33		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		724701 MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		1113845 GRDN_HUMAN (116-772): 9.29e-12: 71.4: 11.87		WWP1_HUMAN (3-372): 4.14e-48: 186: 11.66
+	Hs
		808914 CSTFT_HUMAN (76-170): 1.7e-15: 82.5: 29.17		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		551633 DESP_HUMAN (125-772): 9.93e-15: 81: 11.43		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Hs
		725106 MYH10_HUMAN (228-817): 4.57e-14: 78.7: 9.49		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Mm
		809064 CTRO_MOUSE (135-732): 3.76e-12: 72.8: 10.96		YAP1_MOUSE (1-274): 1.47e-43: 167: 15.19
+	Hs
		808624 PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30		YAP1_HUMAN (1-274): 2.65e-43: 166: 14.87
+	Dm
		1373179 Q9VRM6_DROME (256-631): 5.41e-15: 82: 16.58		SUDX_DROME (69-385): 2.54e-36: 150: 12.94
+	Dm
		54898 A1ZA72_DROME (290-789): 6.25e-09: 62.1: 12.67		SUDX_DROME (69-385): 2.54e-36: 150: 12.94
+	Dm
		54872 A1ZA72_DROME (290-789): 6.25e-09: 62.1: 12.67		YAP1_DROME (5-274): 2.19e-33: 135: 11.62