HitPredict

Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB

Interactor 2: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23211419
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 651 Hs			1 142
+	Hs
		833639 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22
+	Rn
		950916 Q3MUI1_RAT (1-651): 2.15e-78: 262: 83.13		AP2M1_RAT (1-138): 1.82e-41: 144: 15.22
+	Hs
		1287523 GULP1_HUMAN (4-301): 1.98e-53: 187: 20.46		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22
+	Mm
		915571 ANS1B_MOUSE (7-213): 4.87e-48: 184: 18.75		AP2S1_MOUSE (1-142): 6.18e-46: 147: 100.00
+	Ce
		283750 CED6_CAEEL (7-402): 5.6e-36: 143: 14.85		AP2M_CAEEL (1-138): 2.47e-43: 149: 15.94
+	Hs
		253596 CAPON_HUMAN (8-286): 2.51e-35: 141: 17.11		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22
+	Hs
		957208 DAB2_HUMAN (31-643): 9.53e-33: 136: 14.01		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22