HitPredict

Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 651 Hs			1 244
+	Hs
		833550 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RND2_HUMAN (20-244): 3.9e-103: 300: 64.00
+	Hs
		436206 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48
+	Hs
		833635 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RND1_HUMAN (1-244): 1.22e-90: 268: 58.20
+	Hs
		833570 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Hs
		833560 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		833571 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		545266 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89
+	Hs
		833562 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Hs
		833559 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		833576 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47
+	Hs
		120348 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18
+	Hs
		833660 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		564452 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02
+	Hs
		900638 ANS1B_HUMAN (7-215): 9.71e-51: 192: 19.05		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Mm
		1206680 ANS1B_MOUSE (7-213): 4.87e-48: 184: 18.75		RAB1B_MOUSE (16-241): 7.83e-77: 232: 22.47
+	Mm
		892714 ANS1B_MOUSE (7-213): 4.87e-48: 184: 18.75		RAC3_MOUSE (24-199): 1.42e-75: 229: 43.75
+	Hs
		925491 ANS1A_HUMAN (8-244): 1.9e-39: 158: 18.49		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		892522 ANS1A_HUMAN (8-244): 1.9e-39: 158: 18.49		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		1335432 NUMBL_HUMAN (1-651): 4.19e-48: 180: 45.55		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		564765 NUMBL_HUMAN (1-651): 4.19e-48: 180: 45.55		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02