HitPredict

Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 651 Hs			1 232
+	Hs
		833563 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		833560 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		833550 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		833571 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		833559 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		833569 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545266 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		833562 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		833576 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436206 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		833570 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120348 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		833660 NUMB_HUMAN (1-651): 7.18e-103: 328: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		900638 ANS1B_HUMAN (7-215): 9.71e-51: 192: 19.05		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Mm
		892714 ANS1B_MOUSE (7-213): 4.87e-48: 184: 18.75		RAC3_MOUSE (11-188): 5.54e-77: 232: 39.89
+	Mm
		1206680 ANS1B_MOUSE (7-213): 4.87e-48: 184: 18.75		RAB1B_MOUSE (7-229): 3.8e-76: 230: 21.33
+	Hs
		914507 NUMBL_HUMAN (1-651): 4.19e-48: 180: 45.55		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		925491 ANS1A_HUMAN (8-244): 1.9e-39: 158: 18.49		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892522 ANS1A_HUMAN (8-244): 1.9e-39: 158: 18.49		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		1335432 NUMBL_HUMAN (1-651): 4.19e-48: 180: 45.55		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21