Interactor 1: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB

Interactor 2: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.680

The method score is based on:

Property Details
Experiments 12682059, 18628966, 20818436
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0031410 - cytoplasmic vesicle
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 651
Hs

1 903
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024