HitPredict

Interactor 1: RGS6 (P49758)
Regulator of G-protein signaling 6 (RGS6) (S914)
Gene: RGS6

Interactor 2: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10339615
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEP~WD40, G-gamma~WD40, RGS~WD40, RGS_DHEX~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 340
+	Hs
		833679 RGS6_HUMAN (1-472): 0: 692: 100.00		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		833678 RGS6_HUMAN (1-472): 0: 692: 100.00		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		560862 RGS6_HUMAN (1-472): 0: 692: 100.00		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		154664 RGS6_HUMAN (1-472): 0: 692: 100.00		GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08
+	Hs
		154665 RGS7_HUMAN (1-466): 0: 627: 72.16		GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08
+	Ce
		184654 O17589_CAEEL (23-461): 8.18e-150: 437: 34.52		GBB1_CAEEL (1-340): 6e-107: 317: 84.71
+	Hs
		154648 RGS9_HUMAN (17-466): 0: 563: 37.75		GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08
+	Mm
		222406 RGS9_MOUSE (17-466): 0: 551: 36.65		GNB5_MOUSE (129-340): 9.12e-43: 154: 23.53
+	Bt
		60988 RGS9_BOVIN (17-466): 0: 552: 37.53		A5PJS1_BOVIN (129-340): 8.12e-43: 153: 22.62
+	Hs
		154649 RGS11_HUMAN (22-464): 0: 540: 35.87		GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08
+	Ce
		184655 O17589_CAEEL (23-461): 8.18e-150: 437: 34.52		GBB2_CAEEL (129-340): 3.57e-45: 159: 22.83
+	Ce
		567430 EGL10_CAEEL (255-460): 1.7e-65: 222: 39.82		GBB1_CAEEL (1-340): 6e-107: 317: 84.71
+	Ce
		834951 EGL10_CAEEL (255-460): 1.7e-65: 222: 39.82		GBB2_CAEEL (129-340): 3.57e-45: 159: 22.83