HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: BCLF1 (Q9NYF8)
Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Gene: BCLAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	28514442, 33961781, 32707033, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 920
+	Hs
		833824 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		834136 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		625615 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		1268600 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		833911 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		833761 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		833996 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		833842 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		1044201 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		834072 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		1191723 CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		834151 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		1044295 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		69425 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		B0AZU3_HUMAN (783-920): 5.5e-16: 77.7: 100.00
+	Hs
		625528 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Hs
		1264773 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Ce
		246633 MBK2_CAEEL (145-487): 5.44e-111: 349: 27.93		O61201_CAEEL (117-779): 4.88e-10: 66.2: 14.35
+	Hs
		1044321 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		PCLO_HUMAN (96-875): 9.08e-13: 75: 10.41