HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 923
+	Hs
		833847 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		834156 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		162338 CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Xl
		724509 CDK1A_XENLA (160-484): 5.53e-115: 342: 24.63		Q6NS03_XENLA (3-918): 4.57e-148: 467: 12.80
+	Hs
		162721 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Sp
		534546 HOG1_SCHPO (158-498): 7.02e-112: 336: 23.12		XPO1_SCHPO (3-920): 1.66e-123: 402: 13.26
+	Hs
		312184 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63