HitPredict

Interactor 1: CLK3 (P49761)
Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)
Gene: CLK3

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.50	0.662

Property	Details
Experiments	35271311, 28514442, 33961781, 32707033, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 923
+	Hs
		833847 CLK1_HUMAN (149-625): 1.2e-137: 412: 48.67		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		834000 CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		162721 DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162338 CDK1_HUMAN (301-624): 5.68e-119: 357: 24.70		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Xl
		724509 CDK1A_XENLA (301-634): 4.3e-121: 363: 24.85		Q6NS03_XENLA (3-918): 4.57e-148: 467: 12.80
+	Hs
		312184 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		IPO7_HUMAN (13-813): 8.63e-101: 340: 11.63
+	Zm
		5535 A0A1D6E0J9_MAIZE (303-636): 4.48e-39: 156: 29.79		A0A1D6LCD9_MAIZE (3-918): 2.09e-148: 469: 12.67