Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Interactor 2: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 32814053
Identification Methods validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0098794 - postsynapse
GO:0098978 - glutamatergic synapse
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 467
Hs

1 937
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024