Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Interactor 2: ECSIT (Q9BQ95)
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
Gene: ECSIT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.59 0.60 0.599

The method score is based on:

Property Details
Experiments 21163940
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 467
Hs

1 431
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024