Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1
Interactor 2: TREM2 (Q9NZC2)
Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)
Gene: TREM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 0.55 | 0.530 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29611543 |
| Identification Methods | anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001934 - positive regulation of protein phosphorylation GO:0005886 - plasma membrane GO:0007613 - memory GO:0008013 - beta-catenin binding GO:0009986 - cell surface and 6 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
