Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1
Interactor 2: MTCH1 (Q9NZJ7)
Mitochondrial carrier homolog 1 (Presenilin-associated protein)
Gene: MTCH1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 0.55 | 0.458 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12377771 |
Identification Methods | coimmunoprecipitation |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005739 - mitochondrion GO:0016020 - membrane GO:0043065 - positive regulation of apoptotic process |
Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024