Interactor 1: PSN1 (P49769)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: Psen1

Interactor 2: NOTC1 (Q01705)
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: Notch1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 11518718
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0001947 - heart looping
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 15 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 467
Mm

1 2531
+ Hs
+ Mm
+ Mm
+ Dm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024