HitPredict - High confidence protein-protein interactions

Interactor 1: PSN1 (P49769)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: Psen1

Interactor 2: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	20696212, 11104755, 16126725
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001708 - cell fate specification GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005654 - nucleoplasm and 23 others more... GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0007507 - heart development GO:0010467 - gene expression GO:0010629 - negative regulation of gene expression GO:0016020 - membrane GO:0030182 - neuron differentiation GO:0030900 - forebrain development GO:0032991 - protein-containing complex GO:0042734 - presynaptic membrane GO:0043065 - positive regulation of apoptotic process GO:0043198 - dendritic shaft GO:0043524 - negative regulation of neuron apoptotic process GO:0045296 - cadherin binding GO:0045893 - positive regulation of DNA-templated transcription GO:0048538 - thymus development GO:0050808 - synapse organization GO:0097190 - apoptotic signaling pathway GO:0098609 - cell-cell adhesion GO:0098978 - glutamatergic synapse GO:2001234 - negative regulation of apoptotic signaling pathway
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	467
Mm

1	781

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Last updated: 15 Jul 2024