HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: NTF2 (P61970)
Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15)
Gene: NUTF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	15522285, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0017056 - structural constituent of nuclear pore GO:0031965 - nuclear membrane and 1 others more... GO:0051028 - mRNA transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 127
+	Hs
		834687 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93
+	Hs
		834733 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		834707 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		NTF2_HUMAN (1-127): 3.29e-51: 160: 100.00
+	Hs
		834852 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		NXT2_HUMAN (6-123): 6.69e-39: 129: 24.22
+	Hs
		63884 RGPD3_HUMAN (1136-1440): 4.22e-38: 158: 16.39		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		727246 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		727332 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93
+	Hs
		727234 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		NTF2_HUMAN (1-127): 3.29e-51: 160: 100.00
+	Hs
		152807 RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72		NXT2_HUMAN (6-123): 6.69e-39: 129: 24.22
+	Hs
		1030534 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		1354857 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93
+	Hs
		727319 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		NXT2_HUMAN (6-123): 6.69e-39: 129: 24.22
+	Hs
		1293170 P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24		G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93
+	Hs
		857971 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		1354807 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		NXT1_HUMAN (6-123): 2.94e-38: 127: 23.44
+	Sc
		541862 NSP1_YEAST (861-1373): 2.64e-12: 73.7: 18.15		NTF2_YEAST (3-122): 3.22e-42: 137: 42.62
+	Dm
		1358685 NU214_DROME (72-907): 3.82e-10: 67.1: 8.85		NXT1_DROME (9-123): 9.5e-35: 118: 27.27