HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26496610, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 330
+	Hs
		737655 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		905894 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		906185 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		930846 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30
+	Hs
		738105 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		906621 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		738130 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Dm
		113980 M9PB30_DROME (77-757): 6.74e-17: 89.5: 9.05		PP1B_DROME (6-326): 0: 551: 83.49
+	Hs
		931030 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30