HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol GO:0031965 - nuclear membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 101
+	Hs
		834572 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		902585 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		834712 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		834705 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Sp
		140919 NU124_SCHPO (702-1470): 4.84e-40: 164: 11.67		PMT3_SCHPO (2-99): 1.41e-36: 121: 51.02
+	Ce
		879074 Q86G90_CAEEL (820-1172): 8.96e-35: 146: 18.11		SUMO_CAEEL (9-97): 4.4e-34: 114: 58.43
+	Hs
		727233 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Ce
		879066 Q21021_CAEEL (446-997): 6.85e-30: 130: 12.06		SUMO_CAEEL (9-97): 4.4e-34: 114: 58.43
+	Hs
		928221 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00
+	Hs
		902790 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Hs
		902642 SRCAP_HUMAN (167-984): 6.22e-20: 99.5: 9.62		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Sc
		691672 NUP2_YEAST (923-1394): 5.12e-24: 111: 17.83		SMT3_YEAST (3-99): 7.04e-32: 109: 47.42
+	Hs
		1241453 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		NF2IP_HUMAN (10-90): 2.19e-25: 99.4: 26.83
+	Hs
		1170070 SRCAP_HUMAN (167-984): 6.22e-20: 99.5: 9.62		NF2IP_HUMAN (10-90): 2.19e-25: 99.4: 26.83
+	Hs
		902812 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36
+	Sc
		541932 NSP1_YEAST (861-1373): 2.64e-12: 73.7: 18.15		SMT3_YEAST (3-99): 7.04e-32: 109: 47.42