HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1475 Hs			1 768
+	Hs
		834596 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		834741 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042256 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		152778 RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042166 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		727251 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042858 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Dm
		1359795 Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02		Q9V475_DROME (2-768): 0: 861: 68.77
+	Hs
		1043127 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		834739 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1043482 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		727252 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043279 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043633 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		834740 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041250 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041413 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		727250 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041489 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1274074 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CUL5_HUMAN (25-768): 0: 597: 23.77