HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: SENP2 (Q9HC62)
Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2)
Gene: SENP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	26496610, 11896061, 12192048
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031965 - nuclear membrane GO:0051028 - mRNA transport
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 589
+	Hs
		1056994 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		SENP2_HUMAN (1-589): 0: 786: 100.00
+	Hs
		834679 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		SENP1_HUMAN (203-589): 3.75e-114: 355: 40.00
+	Hs
		1335823 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SENP2_HUMAN (1-589): 0: 786: 100.00
+	Hs
		834857 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		SENP1_HUMAN (203-589): 3.75e-114: 355: 40.00
+	Sc
		691659 NUP2_YEAST (923-1394): 5.12e-24: 111: 17.83		ULP1_YEAST (88-588): 1.69e-96: 309: 22.24
+	Sc
		595061 NUP1_YEAST (863-1451): 7.24e-23: 108: 18.05		ULP1_YEAST (88-588): 1.69e-96: 309: 22.24
+	Dm
		1370322 Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02		Q9VWK5_DROME (97-588): 3.24e-81: 280: 23.49
+	Hs
		1326246 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SENP6_HUMAN (479-587): 1.15e-19: 95.7: 22.50