HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: NXF1 (Q9UBU9)
Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)
Gene: NXF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	26496610, 11073998, 29395067, 31375530, 18596238, 20123736, 10668806
Identification Methods	affinity chromatography technology, pull down, proximity labelling technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0042405 - nuclear inclusion body
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 619
+	Hs
		834667 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Hs
		834861 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		1305510 RGPD5_HUMAN (1136-1440): 7.32e-39: 161: 16.72		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		483413 RGPD1_HUMAN (1136-1440): 3.02e-38: 159: 16.07		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		727326 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		1354346 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		1293163 P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		1305503 RGPD5_HUMAN (1136-1440): 7.32e-39: 161: 16.72		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Hs
		858064 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		152806 RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Hs
		727313 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Hs
		1017095 TROP_HUMAN (843-1469): 2.37e-17: 90.6: 13.83		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Dm
		1353485 NU153_DROME (322-1372): 1.72e-11: 71.4: 16.12		NXF1_DROME (20-619): 0: 562: 30.49
+	Dm
		1353486 NU214_DROME (72-907): 3.82e-10: 67.1: 8.85		NXF1_DROME (20-619): 0: 562: 30.49
+	Ce
		1197298 Q86G90_CAEEL (820-1172): 8.96e-35: 146: 18.11		NXF1_CAEEL (127-617): 4.08e-158: 469: 27.70
+	Tt
		101905 NU145_CHATD (865-1304): 7.3e-09: 62.9: 15.28		G0SET4_CHATD (27-618): 1.43e-144: 435: 21.72
+	Sc
		691677 NUP2_YEAST (923-1394): 5.12e-24: 111: 17.83		MEX67_YEAST (121-619): 2.13e-118: 366: 21.64
+	Sc
		595087 NUP1_YEAST (863-1451): 7.24e-23: 108: 18.05		MEX67_YEAST (121-619): 2.13e-118: 366: 21.64
+	Sc
		541937 NSP1_YEAST (861-1373): 2.64e-12: 73.7: 18.15		MEX67_YEAST (121-619): 2.13e-118: 366: 21.64