HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1475 Hs			1 496
+	Dm
		1370339 Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02		FBXW7_DROME (20-496): 6.04e-89: 298: 17.46
+	Hs
		1056932 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1281391 PRR36_HUMAN (694-1451): 1.9e-16: 87.5: 9.67		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1057025 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		834706 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1264784 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1346970 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		1017382 MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Hs
		1288362 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1288235 P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		793042 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		1288394 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1264822 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		1318185 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		TBL1R_HUMAN (98-260): 6.38e-22: 100: 13.22
+	Hs
		1332354 PRR36_HUMAN (694-1451): 1.9e-16: 87.5: 9.67		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Dm
		1358850 NUP98_DROME (905-1380): 3.22e-17: 90.2: 13.12		WDS_DROME (389-496): 1.28e-24: 106: 17.43
+	Hs
		1357196 SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		857957 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1017454 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Hs
		857968 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67