HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0051028 - mRNA transport GO:0140693 - molecular condensate scaffold activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1475 Hs			1 482
+	Hs
		834573 NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00		NTF2_HUMAN (4-139): 2.55e-40: 143: 26.47
+	Hs
		834733 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		727332 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1354857 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		63884 RGPD3_HUMAN (1136-1440): 4.22e-38: 158: 16.39		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1293170 P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		727246 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030534 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		834707 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		NTF2_HUMAN (4-139): 2.55e-40: 143: 26.47
+	Hs
		857971 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		727234 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		NTF2_HUMAN (4-139): 2.55e-40: 143: 26.47
+	Hs
		1073567 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SAFB1_HUMAN (141-482): 2.07e-42: 163: 16.43
+	Hs
		1049537 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		SAFB2_HUMAN (141-482): 1.89e-41: 160: 14.69
+	Hs
		1272122 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Sc
		541862 NSP1_YEAST (861-1373): 2.64e-12: 73.7: 18.15		NTF2_YEAST (10-132): 1.12e-20: 89.2: 28.80