Interactor 1: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 7603572, 21988832, 10318915, 20547757, 11470507, 10078529, 24855949
Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ran_BP1~Ras, Ras~zf-RanBP
Common GO terms GO:0003723 - RNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 3224
Hs

1 216
+ Hs
+ Hs
+ Ce
+ Ce
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+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024