Interactor 1: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 26496610, 28514442, 17353931, 33961781, 20936779, 22194619, 26261240, 19785004, 12192048, 35271311, 15037602, 22464730, 15608651, 11709548
Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IR1-M~UQ_con
Common GO terms GO:0003723 - RNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 3224
Hs

1 158
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024