HitPredict

Interactor 1: PSN2 (P49810)
Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Gene: PSEN2

Interactor 2: CIB1 (Q99828)
Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28)
Gene: CIB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

The method score is based on:

Property	Details
Experiments	10366599, 15475008
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus GO:0005813 - centrosome GO:0005886 - plasma membrane GO:0016020 - membrane and 6 others more... GO:0016324 - apical plasma membrane GO:0030426 - growth cone GO:0043025 - neuronal cell body GO:0043066 - negative regulation of apoptotic process GO:0043085 - positive regulation of catalytic activity GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	448
Hs

1	191

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024