HitPredict

Interactor 1: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 30514904, 12869586, 12820960, 12771962, 17077083, 12842888, 15854902
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Rap_GAP~Ras
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0014069 - postsynaptic density
GO:0016020 - membrane
GO:0051726 - regulation of cell cycle
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1807
Hs

1 184
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024