Interactor 1: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 20166753, 21134130, 28561026, 15851026, 14651849, 15963462, 16424383, 17077083, 14551205, 11741833, 11741832, 11290735, 10807585, 9580671, 10915759, 17658474, 36348010, 11175345, 20169078, 30514904 and 11 others

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Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, protein kinase assay, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001843 - neural tube closure
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
and 10 others

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Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1807
Hs

1 1164
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Sp

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Last updated: 15 Jul 2024