HitPredict

Interactor 1: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Interactor 2: TBCD7 (Q9P0N9)
TBC1 domain family member 7 (Cell migration-inducing protein 23)
Gene: TBC1D7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

The method score is based on:

Property	Details
Experiments	28561026, 17658474, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005096 - GTPase activator activity GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0009267 - cellular response to starvation GO:0031267 - small GTPase binding and 3 others more... GO:0032007 - negative regulation of TOR signaling GO:0033596 - TSC1-TSC2 complex GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	1807
Hs

1	293

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024