HitPredict

Interactor 1: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36779422, 38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 474
+	Hs
		835784 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		625176 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		724714 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		625530 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		625446 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		528401 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH8_HUMAN (28-321): 5.06e-09: 61.1: 10.54
+	Hs
		835769 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		625177 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39
+	Dm
		576356 SGG_DROME (68-456): 1.03e-137: 408: 73.15		Q59E58_DROME (33-428): 1.57e-10: 65.8: 9.85
+	Dm
		576488 SGG_DROME (68-456): 1.03e-137: 408: 73.15		MYSN_DROME (33-428): 2.04e-10: 65.4: 9.85
+	Dm
		576891 SGG_DROME (68-456): 1.03e-137: 408: 73.15		Q9W3V2_DROME (52-329): 1.43e-09: 62.6: 22.33
+	Hs
		528368 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH6_HUMAN (20-389): 4.46e-10: 64.2: 9.00
+	Hs
		502908 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH3_HUMAN (48-349): 1.75e-09: 62.3: 11.88
+	Hs
		960130 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH15_HUMAN (1-355): 2.17e-09: 62.3: 10.03
+	Hs
		528405 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH8_HUMAN (28-321): 5.06e-09: 61.1: 10.54
+	Hs
		522542 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH1_HUMAN (15-321): 8.57e-09: 60.4: 10.10
+	Hs
		522604 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH7_HUMAN (3-404): 7.14e-09: 60.4: 10.67
+	Hs
		960128 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH2_HUMAN (27-306): 9.34e-09: 60: 9.97
+	Hs
		960129 CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50		MYH13_HUMAN (10-371): 9.92e-09: 60: 13.66