Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B
Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.61 | 1.00 | 0.785 |
The method score is based on:
Property | Details |
---|---|
Experiments | 24165324 |
Identification Methods | pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, protein kinase assay |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Pkinase~Pkinase |
Common GO terms | GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 21 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024