HitPredict

Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 975
+	Hs
		724714 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Hs
		625177 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81
+	Hs
		835987 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		SPTN4_HUMAN (6-825): 4.17e-18: 92.3: 13.61
+	Mm
		1351610 GSK3B_MOUSE (1-408): 4.52e-162: 464: 99.02		MACF1_MOUSE (3-493): 8.14e-14: 78.5: 13.16
+	Hs
		836093 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MACF1_HUMAN (3-477): 8.96e-13: 75: 12.55
+	Hs
		835678 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		DYST_HUMAN (1-921): 4.17e-12: 72.9: 9.83
+	Hs
		809086 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		UTRN_HUMAN (4-702): 5.63e-11: 69.2: 12.03
+	Hs
		625176 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Hs
		528401 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH8_HUMAN (351-936): 1.29e-19: 97.2: 10.08
+	Hs
		835567 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		MACF1_HUMAN (3-477): 8.96e-13: 75: 12.55
+	Hs
		835335 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		DYST_HUMAN (1-921): 4.17e-12: 72.9: 9.83
+	Hs
		809085 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		UTRN_HUMAN (4-702): 5.63e-11: 69.2: 12.03
+	Hs
		625418 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		SPTN1_HUMAN (5-666): 4.38e-13: 76: 9.94
+	Dm
		115292 SGG_DROME (1-393): 8.87e-144: 421: 77.16		M9PEP8_DROME (3-929): 1.53e-12: 74.2: 9.83
+	Dm
		576415 SGG_DROME (1-393): 8.87e-144: 421: 77.16		Q7KV70_DROME (7-745): 3.05e-12: 73.3: 13.74
+	Dm
		576831 SGG_DROME (1-393): 8.87e-144: 421: 77.16		Q9VZQ3_DROME (7-745): 3.86e-12: 72.9: 13.74
+	Hs
		625380 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		DYST_HUMAN (1-921): 4.17e-12: 72.9: 9.83
+	Dm
		54307 SGG_DROME (1-393): 8.87e-144: 421: 77.16		A1Z9J3_DROME (110-937): 1.08e-11: 71.8: 11.79
+	Hs
		502908 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH3_HUMAN (351-938): 5.07e-18: 92.2: 9.11
+	Dm
		54285 SGG_DROME (1-393): 8.87e-144: 421: 77.16		A1Z9J1_DROME (4-924): 4.52e-10: 66.1: 10.12