HitPredict

Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: ALMS1 (Q8TCU4)
Centrosome-associated protein ALMS1 (Alstrom syndrome protein 1)
Gene: ALMS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 36779422
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 4168
+	Hs
		835462 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		ALMS1_HUMAN (1-4168): 0: 3024: 100.00
+	Hs
		835945 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		CJ090_HUMAN (4014-4163): 7.68e-43: 172: 39.87
+	Hs
		65021 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		A7Y9J9_HUMAN (29-1947): 7.2e-36: 154: 10.51
+	Dm
		65548 SGG_DROME (1-393): 8.87e-144: 421: 77.16		A8JNM5_DROME (638-2252): 1.06e-40: 170: 9.05
+	Dm
		576908 SGG_DROME (1-393): 8.87e-144: 421: 77.16		FUTSC_DROME (2-2328): 1.1e-33: 146: 7.97
+	Hs
		835653 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MAP1A_HUMAN (545-2307): 6.26e-13: 78: 7.75
+	At
		96276 KSG7_ARATH (28-389): 9.83e-151: 433: 62.81		SYD_ARATH (124-1446): 2.15e-20: 102: 10.37
+	Hs
		554284 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MUC1_HUMAN (466-1359): 6.23e-10: 68: 13.55
+	Hs
		625528 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		TITIN_HUMAN (3-1424): 2e-23: 113: 8.92
+	Hs
		64079 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		L37A2_HUMAN (455-1207): 2.78e-20: 102: 12.10
+	Dm
		115292 SGG_DROME (1-393): 8.87e-144: 421: 77.16		M9PEP8_DROME (349-2120): 2.68e-21: 105: 10.39
+	Dm
		113978 SGG_DROME (1-393): 8.87e-144: 421: 77.16		M9PB30_DROME (32-578): 1.57e-17: 93.4: 6.29
+	Dm
		576465 SGG_DROME (1-393): 8.87e-144: 421: 77.16		SPEN_DROME (28-1791): 3.43e-16: 89.2: 7.19
+	Hs
		835321 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		MAP1A_HUMAN (545-2307): 6.26e-13: 78: 7.75
+	Hs
		625662 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		NCOR2_HUMAN (62-1792): 9.19e-12: 74.4: 9.21
+	Dm
		112382 SGG_DROME (1-393): 8.87e-144: 421: 77.16		M9MSG3_DROME (320-2225): 4.35e-11: 72.1: 8.68
+	Hs
		841300 CDK7_HUMAN (56-374): 2.6e-51: 177: 36.61		MINT_HUMAN (2-1866): 7.27e-45: 183: 9.10