Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: RPGF6 (Q8TEU7)
Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)
Gene: RAPGEF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36779422
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043547 - positive regulation of GTPase activity
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 420
Hs

1 1601
+ Hs
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024