HitPredict

Interactor 1: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 677 Hs			1 726
+	Hs
		631376 TAF6_HUMAN (1-677): 0: 860: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		836238 TAF6_HUMAN (1-677): 0: 860: 100.00		BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71
+	Hs
		836213 TAF6_HUMAN (1-677): 0: 860: 100.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		836260 TAF6_HUMAN (1-677): 0: 860: 100.00		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Hs
		244122 TAF6_HUMAN (1-677): 0: 860: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		836257 TAF6_HUMAN (1-677): 0: 860: 100.00		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Hs
		600101 TAF6_HUMAN (1-677): 0: 860: 100.00		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52
+	Dm
		836175 TAF6_DROME (9-559): 0: 645: 48.56		TAF1_DROME (127-721): 9.05e-17: 87.2: 11.55
+	Sc
		858562 TAF6_YEAST (7-446): 1.55e-161: 476: 28.96		GCN5_YEAST (284-417): 7.13e-37: 145: 31.88
+	Sp
		251532 TAF6_SCHPO (9-415): 7.2e-163: 477: 37.32		YK82_SCHPO (29-148): 6.59e-30: 128: 33.61
+	Mm
		1246827 TAF6L_MOUSE (5-564): 3.03e-155: 464: 20.20		KAT2A_MOUSE (267-414): 7.42e-33: 137: 28.86
+	Hs
		1271478 TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Hs
		1271524 TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67		KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50
+	Sc
		728723 TAF6_YEAST (7-446): 1.55e-161: 476: 28.96		BDF1_YEAST (191-693): 8.87e-19: 93: 14.43
+	Hs
		245145 TAF6L_HUMAN (5-564): 1.8e-144: 436: 19.67		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56