HitPredict - High confidence protein-protein interactions

Interactor 1: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Interactor 2: TAF12 (Q16514)
Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15)
Gene: TAF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	33961781, 35271311, 9133630
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000124 - SAGA complex GO:0003677 - DNA binding GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 13 others more... GO:0005669 - transcription factor TFIID complex GO:0006282 - regulation of DNA repair GO:0006352 - DNA-templated transcription initiation GO:0006357 - regulation of transcription by RNA polymerase II GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0033276 - transcription factor TFTC complex GO:0042789 - mRNA transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription GO:0046695 - SLIK (SAGA-like) complex GO:0046982 - protein heterodimerization activity GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	677
Hs

1	161

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Last updated: 15 Jul 2024