HitPredict

Interactor 1: GRAK (P49863)
Granzyme K (EC 3.4.21.-) (Fragmentin-3) (Granzyme-3) (NK-tryptase-2) (NK-Tryp-2)
Gene: GZMK

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	19059912
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Hs			1 450
+	Hs
		428722 TRY2_HUMAN (4-262): 2.78e-109: 317: 30.89		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		1037390 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		1037427 KLK11_HUMAN (24-261): 2.76e-98: 290: 35.80		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		1037334 KLK6_HUMAN (9-260): 1.21e-97: 287: 33.20		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		381216 PRSS8_HUMAN (5-258): 6.66e-102: 302: 32.72		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		1114233 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428427 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		933971 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		1046575 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB2A_HUMAN (1-430): 0: 700: 93.49
+	Hs
		1312808 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		381298 TMPS5_HUMAN (11-261): 1.03e-97: 295: 31.66		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		420746 KLK1_HUMAN (6-262): 8.98e-98: 288: 27.84		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Mm
		371765 CFAD_MOUSE (5-256): 7.13e-56: 181: 37.80		TBB4B_MOUSE (1-427): 0: 703: 93.91
+	Hs
		595528 GRAH_HUMAN (26-258): 5.66e-44: 150: 39.24		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		595536 GRAH_HUMAN (26-258): 5.66e-44: 150: 39.24		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428017 GRAH_HUMAN (26-258): 5.66e-44: 150: 39.24		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		1114231 KLK15_HUMAN (26-258): 9.54e-42: 145: 36.48		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		381123 GRAH_HUMAN (26-258): 5.66e-44: 150: 39.24		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		439334 CATG_HUMAN (26-258): 1.11e-40: 142: 37.55		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		427973 CATG_HUMAN (26-258): 1.11e-40: 142: 37.55		TBB5_HUMAN (1-429): 0: 704: 93.94