Interactor 1: DNLI4 (P49917)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: LIG4

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 22990118
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0097680 - double-strand break repair via classical nonhomologous end joining
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 911
Hs

1 1972
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024